Nephron-sparing surgery and renal cell carcinoma.

Elective nephron sparing surgery for renal cell carcinoma larger than 4 cm.

PURPOSE Elective nephron sparing surgery is established as an alternative to radical nephrectomy for renal cell carcinoma if tumors are small (4 cm or less, stage T1a). We compared outcomes in patients with renal cell carcinoma 4 cm or less (small) vs more than 4 cm (large) who were treated with nephron sparing surgery. MATERIALS AND METHODS Between 1979 and 2006, 618 patients underwent elect...

Renal Autotransplantation and Extracorporeal Nephron-Sparing Surgery for De Novo Renal Cell Carcinoma in a Kidney Allograft

De novo renal cell carcinoma (RCC) rarely occurs in kidney allografts; however, the risk of RCC in these patients is 100-fold that of the general healthy population. Although total nephrectomy has been the standard treatment for kidney allograft RCC, several authors have reported that early-stage RCC in kidney allografts was successfully treated with nephron-sparing surgery. We herein describe ...

Nephron-Sparing Surgery for the Treatment of Renal Cell Carcinoma 4 to 7 cm in Size

Laparoscopic nephron-sparing surgery in the presence of renal artery disease.

INTRODUCTION To describe the technical considerations of laparoscopic nephron-sparing surgery in 3 complicated cases involving kidneys with renal arterial disease. TECHNICAL CONSIDERATIONS Three candidates for nephron-sparing surgery each had a renal mass, measuring 5.0, 3.5, and 2.5 cm, respectively. The renal arterial pathologic features in the tumor-bearing kidney included renal artery ste...

Managing Renal Cell Carcinoma Associated Paraneoplastic Syndrome with Nephron-sparing Surgery in a Patient with von Hippel-Lindau

A patient with germline von Hippel-Lindau (VHL) gene alteration and history of multiple tumors present with classical paraneoplastic syndrome (PNS) associated with renal cell carcinoma (RCC). She underwent open nephron sparing surgery with resolution of symptoms. She remained without recurrence of RCC for the initial 2 years of her follow-up. To the best of our knowledge, this case represents t...

Localized renal cell carcinoma management: an update.

OBJECTIVE To review the current modalities of treatment for localized renal cell carcinoma. MATERIALS AND METHODS A literature search for keywords: renal cell carcinoma, radical nephrectomy, nephron sparing surgery, minimally invasive surgery, and cryoablation was performed for the years 2000 through 2008. The most relevant publications were examined. RESULTS New epidemiologic data and curr...